John Coffin, Ph.D.

Professor, Tufts University
Program Affiliations: Genetics, Molecular Microbiology

Jaharis, Rm 409
150 Harrison Ave
Boston, MA 02111
Office Phone: 617-636-6528
Lab Phone: 617-636-6526
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Research Interests

In Brief: Molecular biology and evolution of retroviruses

Our research interests revolve around obtaining a better understanding of the interaction of retroviruses with their host cells and organisms. We use simple retroviruses (avian and murine viruses) to elucidate the nature of the retrovirus-receptor interaction; the mechanism and specificity of integration of viral DNA into host DNA; control of viral gene expression; mechanism of retroviral genetic variation; and evolution of the host-virus relationship, as revealed by the fossil record provided by endogenous proviruses found in the normal DNA of all vertebrates and many other species.

http://sackler.tufts.edu/Faculty-and-Research/Find-People-and-Research/Faculty-Profile.aspx?id=32